NII 2

Writable

scientific · also known as NIfTI-2

A Neuroimaging format commonly used in medical industry for the analysis of MRI data. Version 2 is an extended version of NIfTI allowing 64 bit storage and addressing.

Identify it

Extensions	`.nii.nii.gz`
Signatures	`6e6932000d0a1a0a` at byte 4 (The Neuroimaging Informatics Technology Initiative File Format V2 variant1) `6e2b32000d0a1a0a` at byte 4 (The Neuroimaging Informatics Technology Initiative File Format V2 variant2)
PRONOM	`fmt/1094`
Wikidata	`Q28777714`

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Open it

Visualization ToolkitOpen sourcereads and writes · 3-clause BSD License
AFNIOpen sourcereads · GNU General Public License
FreeSurferOpen sourcereads · open-source license
Insight Segmentation and Registration ToolkitOpen sourcereads · Apache Software License 2.0
BrainVoyagerreads
CARETreads
Mangoreads · freeware

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Sources

From Just Solve the File Format Problem (File Formats Wiki), PRONOM, Wikidata. Updated 2026-10-24.

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